In this project, we are working to identify the source of blood clots that cause cryptogenic strokes using RNA-sequencing. We first need to determine the best method to isolate RNA from blood clots by experimenting with artificially created clots using porcine blood. Once that methodology is in place, we will be able to perform RNA isolation on patient blood clots extracted from stroke patients undergoing thrombectomy by our collaborators at UBNS. These RNA samples will then be subjected to RNA-sequencing to characterize the expression profiles of the clots.
Previous wet lab experience and work with RNA is desired. You should be comfortable working with blood. This position provides a great opportunity to gain experience in translational research and work in an interdisciplinary environment.
Disciplines: Biochemistry, bioinformatics and computational biology, biological sciences, biomedical engineering, biomedical sciences, biotechnology, chemical engineering, chemistry, mechanical engineering, medical technology, medicinal chemistry, pharmaceutical scien
Student Skill-Set Needed: Ability to work independently, basic understanding of cell biology, interest in cardiovascular diseases
Available: Fall, Spring, Summer
For further information on this opportunity, or to apply, contact:
Faculty Member: Hui Meng
Department: Mechanical And Aerospace Engineering