Student working on a research project.

Regulation Of Gene Expression

*** ALL POSITIONS FILLED for 2017-2018*** The central dogma of molecular biology states that DNA encodes RNA which encodes proteins. Proteins carry out vital functions within all living cells, and the levels of each protein that is synthesized are tightly regulated. Defects in the control of protein synthesis lead to a number of devastating diseases, most notably aggressive forms of cancer, heart disease, and neurological disorders. Our lab studies the fundamental mechanisms that regulate protein synthesis in the model organism Saccharomyces cerevisiae. We employ a variety of techniques spanning molecular biology, monitoring translation at the level of individual translation factor interactions to looking at the positions of every ribosome in the cell. This project will focus on the role of a translation initiation factor in the regulation of protein synthesis. The student will become proficient in molecular cloning and various assays used in the lab.

Research Project Information

Disciplines: Molecular Biology, Genetics, Biochemistry
Student Skill-Set Needed: Motivation and a positive attitude, basic understanding of biology, computational skills beneficial, able to devote substantial time each week, and a commitment of at least 2 semesters + 1 summer. Please include year, major, and an unofficial transcript i
Compensation: Academic Credit, Volunteer, Work Study
Available: Fall, Spring, Summer


For further information on this opportunity, or to apply, contact:

Faculty Member: Sarah Walker
Title: Assistant Professor
Department: Biological Sciences
Office: 653 Hochstetter Hall
Phone: 7166452272