Student working on a research project.

Cardiovascular Disease And Cancer

Cardiovascular Signaling Pathways, Aging Biology, Tumor Cell Biology. Our group is working on elucidating the molecular mechanisms responsible for cardiac AMP-activated protein kinase (AMPK) activation, novel downstream AMPK targets, and the therapeutic potential of targeting AMPK for the prevention and treatment of myocardial ischemia, cardiac hypertrophy and diabetes. We are also attempting to find out the signaling targets (such as AMPK etc) of natural antioxidants from herb medicine for modulating the redox status of tumor cells and developing strategies for cancer therapy with natural products. One of our long-term goal is to understand the mechanisms that underline the reduced tolerance to ischemia/reperfusion stress seen in the elderly with the hope of devising novel strategies to prevent the decline or boost responsiveness in aged populations.

Research Project Information

Disciplines: Biochemical Pharmacology
Student Skill-Set Needed: Biocchemical analysis, Cardiovascular surgery, Cell culture
Compensation: Academic Credit
Available: Fall, Spring, Summer
Website: http://medicine.buffalo.edu/content/medicine/faculty/profile.html?ubit=jli23

Contact

For further information on this opportunity, or to apply, contact:

Faculty Member: Ji Li
Department: Pharmacology And Toxicology
Office: 615 Biomed Res Bldg
Phone: (716)829-5711
Email: jli23@buffalo.edu