Our laboratory studies the effects of hormones and growth factors on the growth and expression of differentiated function of cultured kidney epithelial cells. Both established cell lines and primary cultures are studied. We are examining the signal transduction mechanisms by which particular growth favors stimulate growth of normal cells and changes which occur upon malignant transformation. The laboratory also studies transcriptional control in response to hormones and growth factors. This involves transient transfection studies, knockdowns with siRNA, the use of lentivirus and chromatin immunoprecitation studies.
Disciplines: biochemistry, cell biology, animal cell culture, growth factors
Student Skill-Set Needed: Lab course in cell and molecular biology
Compensation: Academic Credit, Volunteer, Work Study
Available: Fall, Spring, Summer
For further information on this opportunity, or to apply, contact:
Faculty Member: Mary Taub
Office: 522 BRB