Water Quality Researcher

Karen Beljan, BS '05, Environmental Engineering

A Lake Divided: Modeling DO in Onondaga Lake

Beljan, of Eden, New York, evaluated remediation alternatives to improve the water quality of Onondaga Lake, ultimately helping to develop a method to aerate the lake that would improve the water and ecosystem.

(Photo: KC Kratt, MFA '84)

Cardiovascular Disease And Cancer

Cardiovascular Signaling Pathways, Aging Biology, Tumor Cell Biology

Our group is working on elucidating the molecular mechanisms responsible for cardiac AMP-activated protein kinase (AMPK) activation, novel downstream AMPK targets, and the therapeutic potential of targeting AMPK for the prevention and treatment of myocardial ischemia, cardiac hypertrophy and diabetes. We are also attempting to find out the signaling targets (such as AMPK etc) of natural antioxidants from herb medicine for modulating the redox status of tumor cells and developing strategies for cancer therapy with natural products. One of our long-term goal is to understand the mechanisms that underline the reduced tolerance to ischemia/reperfusion stress seen in the elderly with the hope of devising novel strategies to prevent the decline or boost responsiveness in aged populations.

Research Project Information

Date Open: Oct 28, 2009 to Jul 20, 2010
Suggested Skill Set: Biocchemical analysis, Cardiovascular surgery, Cell culture
Compensation: Credit

Faculty / Professor Contact

Professor(s): Ji Li (jli23@buffalo.edu)
Department: Department of Pharmacology and Toxicology
Address: 615 Biomed Res Bldg
Phone: (716)829-5711
Website: http://www.uwyo.edu/LiLab